In vivo comparison of epithelial responses for S-8 versus JP-8 jet fuels below permissible exposure limit
نویسندگان
چکیده
منابع مشابه
Pulmonary evaluation of permissible exposure limit of syntroleum S-8 synthetic jet fuel in mice.
No current studies have systematically examined pulmonary health effects associated with Syntroleum S-8 synthetic jet fuel (S-8). In order to gain an understanding about the threshold concentration in which lung injury is observed, C57BL/6 male mice were nose-only exposed to S-8 for 1 h/day for 7 days at average concentrations of 0 (control), 93, 352, and 616 mg/m(3). Evaluation of pulmonary fu...
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Dermal exposure to jet fuels has received increased attention with the recent release of newer fuels with novel performance additives. The purpose of these studies was to assess the percutaneous absorption and cutaneous disposition of topically applied (25 microl/5 cm(2)) neat Jet-A, JP-8, and JP-8(100) jet fuels by monitoring the absorptive flux of the marker components 14C naphthalene and (3)...
متن کاملUrinary biomarkers of exposure to jet fuel (JP-8).
Benzene, naphthalene, and 1- and 2-naphthol were measured in urine samples obtained from 322 U.S. Air Force personnel categorized a priori as likely to have low, moderate, or high exposure to jet fuel [jet propulsion fuel-8 (JP-8)]. In postexposure samples, levels of these analytes in the high-exposure group were 3- to 29-fold greater than in the low-exposure group and 2- to 12-fold greater tha...
متن کاملJP-8 jet fuel exposure and divided attention test performance in 1991 Gulf War veterans.
INTRODUCTION Previous research indicates that a large cohort of veterans from the 1991 Gulf War report polysymptomatic conditions. These syndromes often involve neurocognitive complaints, fatigue, and musculoskeletal symptoms, thus overlapping with civilian illnesses from low levels of environmental chemicals, chronic fatigue syndrome, and fibromyalgia. METHODS To test for time-dependent chan...
متن کاملSubchronic JP-8 jet fuel exposure enhances vulnerability to noise-induced hearing loss in rats.
Both laboratory and epidemiological studies published over the past two decades have identified the risk of excess hearing loss when specific chemical contaminants are present along with noise. The objective of this study was to evaluate the potency of JP-8 jet fuel to enhance noise-induced hearing loss (NIHL) using inhalation exposure to fuel and simultaneous exposure to either continuous or i...
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ژورنال
عنوان ژورنال: Toxicology
سال: 2008
ISSN: 0300-483X
DOI: 10.1016/j.tox.2008.09.018